Thermodynamics of Phospholipid Self-Assembly
نویسندگان
چکیده
منابع مشابه
Thermodynamics of phospholipid self-assembly.
Negatively charged phospholipids are an important component of biological membranes. The thermodynamic parameters governing self-assembly of anionic phospholipids are deduced here from isothermal titration calorimetry. Heats of demicellization were determined for dioctanoyl phosphatidylglycerol (PG) and phosphatidylserine (PS) at different ionic strengths, and for dioctanoyl phosphatidic acid a...
متن کاملThermodynamics of Self - Assembly L
Self-assembly of molecules to form much larger colloidal or nanosized aggregates has received a great deal of attention the last decades or so and the number of technical applications and products based on the principle of self-assembly is still rapidly increasing. Moreover, fundamental processes in life sciences such as the properties and stability of lipid membranes and their interactions wit...
متن کاملEquation of State for Phospholipid Self-Assembly.
Phospholipid self-assembly is the basis of biomembrane stability. The entropy of transfer from water to self-assembled micelles of lysophosphatidylcholines and diacyl phosphatidylcholines with different chain lengths converges to a common value at a temperature of 44°C. The corresponding enthalpies of transfer converge at ∼-18°C. An equation of state for the free energy of self-assembly formula...
متن کاملChiral Self-Assembly of Nanotubules and Ribbons from Phospholipid Mixtures
Nanoscale structures have been found to self-assemble in a binary mixture of a long-chain, diacetylenic phospholipid and a short chain, saturated lipid. We observe unusual chiral-optical signatures of nanotubule, twisted ribbon, and microtubule morphologies that can be used to monitor their temporal and thermal stability. Circular dichroism results suggest that chiral packing of the lipids driv...
متن کاملChemical Synthesis and Self-Assembly of a Ladderane Phospholipid.
Ladderane lipids produced by anammox bacteria constitute some of the most structurally fascinating yet poorly studied molecules among biological membrane lipids. Slow growth of the producing organism and the inherent difficulty of purifying complex lipid mixtures have prohibited isolation of useful amounts of natural ladderane lipids. We have devised a highly selective total synthesis of ladder...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2012.01.049